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Category Archives: Effects of Cushing’s

Cardiovascular Complications of Cushing’s Syndrome

Cushing’s syndrome is characterized by chronic overproduction of cortisol by the adrenal glands. The most frequent cause of Cushing’s syndrome is a benign pituitary tumor (adenoma) that produces adrenocorticotropic hormone (ACTH), which, in turn, stimulates the adrenal glands. Other causes are tumors elsewhere in the body that produce ACTH and adrenal tumors that produce cortisol.Continue Reading

Steroid Induced Osteoporosis

Excessive production of cortisol by the body or chronic use of corticosteroids (CS) for treatment of disease causes accelerated bone loss and in about 30% of patients it causes osteoporosis related fractures. The first fractures usually occur in the vertebrae. Corticosteroid-induced osteoporosis (CIO) results from multiple effects on calcium and bone metabolism. CS inhibits theContinue Reading

Osteoporosis and Pituitary Disease

Osteoporosis is a common, multifactorial disorder clearly associated with increased morbidity and mortality. It has only been recognized relatively recently that because of the complex hormone disorders which accompany pituitary disease, patients with this condition are at higher risk for the development of osteoporosis and fractures. Patients with pituitary disease should be evaluated for theContinue Reading

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