Print Friendly, PDF & Email

Affective Alterations in Patients with Cushing’s Syndrome in Remission are Associated with Decreased Brain Derived Neurotrophic Factor and Cortisone Levels

Background Affective alterations, including anxiety, emotional lability and apathy might persist in patients who suffered Cushing’s, even long after correction of cortisol excess. Studies using magnetic resonance imaging showed some alterations in the brain of patients in remission for Cushing’s. These alterations were mainly at those regions (hippocampus and prefrontal cortex) in which cortisol actsContinue Reading

Vascular Health in Patients in Remission of Cushing’s Syndrome is Comparable with that in Healthy People when Comorbidities are Treated Adequately

Many patients are asking if they have a higher cardiovascular risk as a result of Cushing’s. This article will focus on this question in a group of patients in long-term remission of Cushing’s syndrome.Continue Reading

Cushing’s and Osteoporosis

Editor’s Note: This article uses the term Cushing’s syndrome, which includes all forms of Cushing’s, including Cushing’s Disease. Cushing’s syndrome has multiple effects on bone metabolism. Elevated cortisol levels directly inhibit bone formation and indirectly influence the skeleton via effects on reproductive hormones, growth hormone, muscle and fat tissue, intestinal calcium absorption, and renal calciumContinue Reading

Long-term Effects of Cushing’s Syndrome on Adipose Tissue Distribution

“Doctor, since I was successfully treated for Cushing’s syndrome, I have lost a lot of weight but my abdominal fat will just not go away.” This is a sentence that many endocrinologists frequently hear, and something you, as patients, may also recognize. This article will focus on the long-term effects of pituitary or adrenal Cushing’sContinue Reading

Questions about Cushing’s and the Brain

An article titled Hypercortisolism and Memory Impairment appeared in the Spring, 2014 issue of the CSRF newsletter and prompted some questions from our members. Question: The article mentions “memory exercises”. What exercises would be recommended and why would they be helpful? Answer: Our brain is like a muscle, it needs regular exercise to stay inContinue Reading