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For Medical Professionals


Diagnostic Tests for Children Who Are Referred for the Investigation of Cushing Syndrome
Dalia L. Batista, MD, Jehan Riar, BS, Meg Keil, RNP, Constantine A. Stratakis, MD, DSc
Pediatrics. 2007 Sep;120(3):e575-86. Epub 2007 Aug 13.

Quality of Life in Children and Adolescents One Year After Cure of Cushing Syndrome: A Prospective Study
Keil MF, Merke DP, Gandhi R, Wiggs EA, Obunse K, Stratakis CA.
Clin Endocrinol (Oxf). 2009 Sep;71(3):326-33. doi: 10.1111/j.1365-2265.2008.03515.x. Epub 2008 Dec 17

Quality of life and other outcomes in children treated for Cushing syndrome
Keil, MF
J Clin Endocrinol Metab. 2013 Jul;98(7):2667-78. doi: 10.1210/jc.2013-1123. Epub 2013 May 2. Review.


Diagnosis and Testing Articles

The Diagnosis of Cushing’s Syndrome: An Endocrine Society Clinical Practice Guideline
Nieman LK, Biller BM, Findling JW, Newell-Price J, Savage MO, Stewart PM, Montori VM.
J Clin Endocrinol Metab. 2008 May;93(5):1526-40. doi: 10.1210/jc.2008-0125. Epub 2008 Mar 11.

Update on late-night salivary cortisol for the diagnosis of Cushing’s syndrome: methodological considerations
Raff H.
Endocrine. 2013 Oct;44(2):346-349. Epub 2013 Jul 10.

Assessment of the utility of the high-dose dexamethasone suppression test in confirming the diagnosis of Cushing disease
Aytug S, Laws ER Jr, Vance ML.
Endocr Pract. 2012 Mar-Apr;18(2):152-7. doi: 10.4158/EP11179.OR.

A physiologic approach to diagnosis of the Cushing syndrome.
Raff H, Findling JW.
Ann Intern Med. 2003 Jun 17: 138(12):980-91.

Medical Articles

Long-Term Impaired Quality of Life in Cushing’s Syndrome despite Initial Improvement after Surgical Remission
John R. Lindsay, Tonya Nansel, Smita Baid, Julie Gumowski, and Lynnette K. Nieman
J Clin Endocrinol Metab. 2006 Feb;91(2):447-53. Epub 2005 Nov 8.

Treatment of ACTH-dependent Cushing’s Syndrome: A Consensus Statement
Biller BM, Grossman AB, Stewart PM, Melmed S, Bertagna X, Bertherat J, Buchfelder M, Colao A, Hermus AR, Hofland LJ, Klibanski A, Lacroix A, Lindsay JR, Newell-Price J, Nieman LK, Petersenn S, Sonino N, Stalla GK, Swearingen B, Vance ML, Wass JA, Boscaro M.
J Clin Endocrinol Metab. 2008 Jul;93(7):2454-62. doi: 10.1210/jc.2007-2734. Epub 2008 Apr 15.

Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing’s syndrome
Maria Fleseriu, Beverly M. K. Biller, James W. Findling, Mark E. Molitch, David E. Schteingart, and Coleman Gross, on behalf of the SEISMIC Study Investigators
J Clin Endocrinol Metab. 2012 Jun;97(6):2039-49. doi: 10.1210/jc.2011-3350. Epub 2012 Mar 30.

A 12-month phase 3 study of pasireotide in Cushing’s disease
Colao A, Petersenn S, Newell-Price J, Findling JW, Gu F, Maldonado M, Schoenherr U, Mills D, Salgado LR, Biller BM; Pasireotide B2305 Study Group
N Engl J Med. 2012 Mar 8;366(10):914-24. doi: 10.1056/NEJMoa1105743

Results of Gamma Knife surgery for Cushing’s disease
Sheehan JP, Xu Z, Salvetti DJ, Schmitt PJ, Vance ML
J Neurosurg. 2013 Aug 9. [Epub ahead of print]

Delayed remission after transsphenoidal surgery in patients with Cushing’s disease
Valassi E, Biller BM, Swearingen B, Pecori Giraldi F, Losa M, Mortini P, Hayden D, Cavagnini F, Klibanski A
J Clin Endocrinol Metab. 2010 Feb;95(2):601-10. doi: 10.1210/jc.2009-1672. Epub 2010 Jan 15

Cushing’s Syndrome
Guest Editor: J.W. Findling and H. Raff
Endocrinol Metab Clin North Am.  June 2005 (Vol. 34, Issue 2)


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