Question: Is Cushing’s hereditary? Dr. Lacroix – For adrenal causes of Cushing’s syndrome, there are some genetic forms. One is with micronodular adrenal dysplasia, sometimes with other tumors, called Carney Complex, where familial cases and responsible genes are now known. This is also true with ACTH-independent bilateral macronodular adrenal hyperplasia as there are now more… Continue Reading
Category Archives: Doctor’s Articles
Do I have Cushing’s? A physician’s perspective
This is a very personal commentary, based on over 25 years of work with patients with pituitary and adrenal problems, particularly Cushing’s syndrome and Cushing’s disease. I have also been fortunate to conduct many research and treatment studies in patients with pituitary disorders and to be part of a dedicated Neuroendocrine (Pituitary) group of Neuroendocrinologists… Continue Reading
Adult Growth Hormone Deficiency
Patients who have had pituitary surgery or radiation for the treatment of Cushing’s Disease, or whom have large pituitary adenomas, are at risk for adult growth hormone (GH) deficiency. Following pituitary surgery or radiation, if a patient is already lacking normal secretion of three or four pituitary hormones, then there is a 95% chance that the patient is GH deficient. In patients who have had pituitary surgery or radiation, there is a 25% chance that the patient will be GH deficient even if secretion of other pituitary hormones is normal.… Continue Reading
Post-Operative Care After Treatment for Cushing’s
What should happen after successful treatment for Cushing’s? As anyone who has had Cushing’s knows, recovery is slow and frustrating. However, patients may not know what to expect regarding post-operative care, particularly about steroid replacement. Surgery for Cushing’s is not like having a gall bladder removed – once the gall bladder is gone, the problem… Continue Reading
An Update on Improved Glucocorticoid Replacement, Summer, 2009
To briefly review, what are the issues with cortisol replacement in individuals who are adrenal insufficient? In normal individuals, cortisol is the highest in the morning and the lowest around mid-night. While replacement doses of hydrocortisone, taken 2 or 3 times daily, provide the body with needed cortisol, the replacement dose does not mimic the… Continue Reading
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