Adult GH deficiency most often occurs following pituitary surgery or radiation. Whenever pituitary surgery or radiation is performed, there is a risk that normal secretion of pituitary hormones will be affected. Of all of the pituitary hormones, secretion of GH appears to be the most easily impaired. If a patient is lacking normal secretion of three or four pituitary hormones, there is a 95% chance that the patient is GH deficient. In patients who have had pituitary surgery or radiation, there is a 25% chance that the patient will be GH deficient even if secretion of other pituitary hormones is normal.… Continue Reading