Category Archives: Doctor’s Articles

Hypercortisolism and Memory Impairment

Doctor's Articles | Published on: Sep 23, 2014 | Effects of Cushing's

Introduction Memory issues in Cushing’s patients have been reported in the literature over the years however, the number of studies addressing this issue is limited. With the fairly recent advent of new imaging techniques, investigators can now study both the physical structure of the brain and brain metabolites (biochemical compounds) in greater detail using non-invasive… Continue Reading

An Update on Medications Used to Treat Cushing’s

Doctor's Articles | Published on: Dec 20, 2013 | Medications for Cushing's

For the majority of individuals with Cushing’s syndrome (CS), surgery directed at the pituitary or adrenal glands is the first and most important treatment; however, many patients do not have a sustained remission after surgery. As a result, treatment options other than surgery are needed for many patients with CS. Until recently, the use of… Continue Reading

Persistent Cushing’s Disease After Unsuccessful Surgery – Assessment and Strategies

Doctor's Articles | Published on: Nov 13, 2013 | Recurrent Pituitary Cushing's

One of the greatest disappointments, both for the patient and the surgeon, is when transsphenoidal surgery is done to treat Cushing’s Disease and there is failure to cure. Although about 90% of microadenomas and about 55% of macroadenomas are successfully treated by an initial transsphenoidal operation, failure to obtain remission and recurrence can develop in… Continue Reading

Cushing’s Syndrome and Bariatric Surgery

Doctor's Articles | Published on: Sep 23, 2013 | Weight Loss, Diet & Exercise

Most patients with Cushing’s syndrome not only experience weight gain but also develop health complications, such as diabetes mellitus and hypertension. These complications overlap with those seen in patients who seek surgery for weight loss (bariatric surgery). Expert recommendations from many medical societies, including the American Association of Clinical Endocrinologists, Obesity Society, American Society for… Continue Reading

Cardiovascular Complications of Cushing’s Syndrome

Doctor's Articles | Published on: Sep 16, 2013 | Effects of Cushing's

Cushing’s syndrome is characterized by chronic overproduction of cortisol by the adrenal glands. The most frequent cause of Cushing’s syndrome is a benign pituitary tumor (adenoma) that produces adrenocorticotropic hormone (ACTH), which, in turn, stimulates the adrenal glands. Other causes are tumors elsewhere in the body that produce ACTH and adrenal tumors that produce cortisol.… Continue Reading