Question: What is the recurrence rate for Cushing’s Disease?

Answer: Transsphenoidal surgery is the initial treatment of choice for most patients with proved or highly suspected Cushing’s disease. Published reports demonstrate that, in experienced centers, remission following surgery can be expected in 80-90% of patients with microadenomas and 50-65% of patients with macroadenomas. Recurrent hypercortisolism can be expected in about 10% of patients with microadenomas and one-third of patients with macroadenomas who enter remission after surgery.

By Dr. Lewis Blevins MD (Winter, 2012)