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Adrenal Tumor Cushing’s Diagnosis

Question: I have an adrenal tumor and signs and symptoms of Cushing’s. Diagnosis is proving challenging. I am looking for an experienced endocrinologist to obtain a diagnosis. Should I contact one of the major pituitary centers or am I looking for an adrenal expert?  Answer: Most pituitary endocrinologists see Cushing’s patients no matter whether itContinue Reading

Bilateral Adrenal Tumors

Question: How common are bilateral adrenal adenomas? Is there a way to tell if the adenomas on both glands are functional? Could this actually be bilateral adrenal hyperplasia? Answer: Almost certainly bilateral adenomas are a form of hyperplasia, which I have called type-I macronodular hyperplasia. I suppose there could be the individual patient where thisContinue Reading

Bipolar Disorder and Psychosis Symptoms

Question: How many patients with active Cushing’s have bipolar disorder? Also, are psychotic symptoms very common?  Answer: This is great question. I will start by including short definitions of bipolar illness and psychosis. According to the National Institute of Mental Health (NIMH), “Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causesContinue Reading

Blood Sugar and the Dexamethasone Suppression Test

Question: I am being tested for Cushing’s and my blood sugars are already running 400-600. I have been asked to do an overnight dexamethasone suppression test. I am afraid that the dex will further increase my blood sugar. Do you have any suggestions? Answer: Dexamethasone can increase blood sugar. You definitely should not receive dexamethasoneContinue Reading

Changes in Cushing’s Medical Community Over Last 15 Years

Question:  If you have been in practice for 15 years or more, what changes have you seen in the Cushing’s medical community regarding treatment, medical therapies, theories on causes, etc.?  Before we had any medications available, what did Cushing’s patients do if surgery and/or radiation didn’t work or they weren’t a candidate for either? Answer: Continue Reading