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Category Archives: Doctor’s Articles


This year marked the 100th anniversary of the Endocrine Society’s Annual Meeting and Expo. The event was held over several gorgeous days in Chicago from March 17-20. Endocrinologists, scientists, nurses, medical students, and other stakeholders gathered in the mutual pursuit of the latest theories, research, and developments in endocrinology. As in previous years, the CSRFContinue Reading

What’s New in Cushing’s Research? A Conversation with Dr. Constantine Stratakis of the NICHD

Dr. Stratakis gave one of the most highly rated presentations at the October 2017 Patient Education Day at the NIH in Bethesda, MD, when he discussed new strategies, research, and outcomes for Cushing’s in his breakout session.  The positive feedback led to our desire to share a version of this presentation in the newsletter.  WhatContinue Reading

Why Can Cortisol Make Us Obese?

Professor Onno C. Meijer, PhD, Einthoven Laboratory, Leiden University Medical Center, Leiden, The Netherlands Cushing’s Syndrome is what happens when we are exposed to (way) too much cortisol, or its synthetic variants. Out of the many unwanted aspects of Cushing’s, fat accumulation is the most visible one, and also one of the biggest risks forContinue Reading

Affective Alterations in Patients with Cushing’s Syndrome in Remission are Associated with Decreased Brain Derived Neurotrophic Factor and Cortisone Levels

Background Affective alterations, including anxiety, emotional lability and apathy might persist in patients who suffered Cushing’s, even long after correction of cortisol excess. Studies using magnetic resonance imaging showed some alterations in the brain of patients in remission for Cushing’s. These alterations were mainly at those regions (hippocampus and prefrontal cortex) in which cortisol actsContinue Reading

Inferior Petrosal Sinus Sampling in the Diagnosis of Cushing’s Disease

Inferior Petrosal Sinus Sampling (IPSS) plays a vital role in the diagnosis and treatment of Cushing’s disease. Cushing’s disease/Cushing’s syndrome is one of the most challenging diagnosis’ in all of Endocrinology. Testing to aid in the diagnosis can be extensive, time consuming, and can take months to complete. Initially, hypercortisolemia (overproduction of cortisol in theContinue Reading


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