Most patients with Cushing’s disease are successfully treated by transsphenoidal pituitary surgery and most cases of adrenal based Cushing’s syndrome require the removal of only one adrenal gland. In cases such as these, adrenal insufficiency (lack of sufficient hormone production from the adrenal glands) is almost always temporary and patients usually recuperate within one year.… Continue Reading
Category Archives: Doctor’s Articles
Vascular Health in Patients in Remission of Cushing’s Syndrome is Comparable with that in Healthy People when Comorbidities are Treated Adequately
Many patients are asking if they have a higher cardiovascular risk as a result of Cushing’s. This article will focus on this question in a group of patients in long-term remission of Cushing’s syndrome.… Continue Reading
Adrenal Insufficiency and Cushing’s
Following successful surgical treatment for Cushing’s, either by removal of a pituitary tumor, one or both adrenal glands or ectopic tumor, most patients are adrenal insufficient (cannot make cortisol) for a period of time. Cortisol is essential to life so patients require replacement with a glucocorticoid, such as hydrocortisone or sometimes prednisone. Most patients recovering from Cushing’s require replacement medication only until their body is able to produce adequate cortisol.… Continue Reading
An Update on Pituitary Surgery for Cushing’s Disease
Introduction Although there are now several new methods for the medical management of Cushing’s disease, for patients who have progressive severe signs and symptoms, surgery provides the best chance of a long lasting remission. Making the diagnosis of a pituitary tumor secreting excess levels of ACTH as the cause of Cushing’s disease can be complicated,… Continue Reading
Salivary Cortisol Test for Cushing’s Syndrome
Cushing’s syndrome — endogenous hypercortisolism — is characterized by a loss of normal 24 hour rhythm in cortisol secretion (circadian rhythmicity). In healthy patients, cortisol levels peak in the early morning hours and decrease to substantially lower levels at night. Rather than the normal decrease in late evening cortisol, patients with Cushing’s syndrome of any… Continue Reading
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