Category Archives: Doctor’s Articles

Summary of the Endocrine Society Clinical Guideline on the Treatment of Cushing’s Syndrome: Part 2

A previous issue of this newsletter covered the first line treatment options for Cushing’s disease and Cushing’s syndrome as outlined in the recently published Endocrine Society guidelines. This summary will discuss the options for treatment in cases of recurrent or persistent Cushing’s disease or in patients where surgery is not an option. Cushing’s Disease Reported… Continue Reading

The Role of Cortisol in Food Intake and Food Choice Behavior: Two Studies in Patients with Cushing’s

Doctor's Articles | Published on: May 23, 2016 | Doctor's Articles, Effects of Cushing's, Weight Loss, Diet & Exercise

Any endocrinologist familiar with Cushing’s hears from patients that the weight gain associated with Cushing’s is unstoppable, even with calorie restriction and exercise. Several factors have been shown to be causal, including cortisol’s direct effects on fat mass, function, and distribution. Specifically, exposure to excess cortisol increases total fat, and abdominal fat in particular, while… Continue Reading

Cushing’s and Osteoporosis

Doctor's Articles | Published on: May 19, 2016 | Doctor's Articles, Effects of Cushing's, Recovery

Editor’s Note: This article uses the term Cushing’s syndrome, which includes all forms of Cushing’s, including Cushing’s Disease. Cushing’s syndrome has multiple effects on bone metabolism. Elevated cortisol levels directly inhibit bone formation and indirectly influence the skeleton via effects on reproductive hormones, growth hormone, muscle and fat tissue, intestinal calcium absorption, and renal calcium… Continue Reading

Summary of The Endocrine Society Guideline on the Treatment of Cushing’s Syndrome: Part 1

Doctor's Articles | Published on: Dec 7, 2015 | Doctor's Articles, Surgery

Editor’s Note: Dr. Lynnette Nieman, NIH, NICHD, Bethesda, MD chaired the task force that developed the guideline. The task force also included Beverly M.K. Biller of Massachusetts General Hospital in Boston, MA; James W. Findling of the Medical College of Wisconsin in Milwaukee, WI; M. Hassan Murad of the Mayo Clinic in Rochester, MN; John… Continue Reading

Long-term Effects of Cushing’s Syndrome on Adipose Tissue Distribution

Doctor's Articles | Published on: Dec 7, 2015 | Doctor's Articles, Recovery, Weight Loss, Diet & Exercise

“Doctor, since I was successfully treated for Cushing’s syndrome, I have lost a lot of weight but my abdominal fat will just not go away.” This is a sentence that many endocrinologists frequently hear, and something you, as patients, may also recognize. This article will focus on the long-term effects of pituitary or adrenal Cushing’s… Continue Reading