Category Archives: Doctor’s Articles

In the Medical Literature

Doctor's Articles | Published on: Jun 8, 2015 | Doctor's Articles, Molecular Mechanism of Cushing's

It is truly an exciting time to be involved in the study of the molecular mechanisms of Cushing’s! From a patient’s perspective, useful treatments for Cushing’s based on new findings will be a long time in coming, however it is highly encouraging to know that many excellent researchers are involved in this research. The Spring,… Continue Reading

Questions about Cushing’s and the Brain

Doctor's Articles | Published on: Jan 21, 2015 | Coping With Cushing's, Recovery

An article titled Hypercortisolism and Memory Impairment appeared in the Spring, 2014 issue of the CSRF newsletter and prompted some questions from our members. Question: The article mentions “memory exercises”. What exercises would be recommended and why would they be helpful? Answer: Our brain is like a muscle, it needs regular exercise to stay in… Continue Reading

Medication Induced Cushing’s

Doctor's Articles | Published on: Jan 21, 2015 | Doctor's Articles, Medication Induced Cushing's

The first therapeutic use of glucocorticoids (i.e., steroid compounds with cortisol activity) in 1948 resulted in dramatic clinical improvement in a patient’s severe rheumatoid arthritis. Almost immediately, however, the potential adverse effects with the development of Cushing’s syndrome became evident. Nevertheless, given the potent anti-inflammatory effects of glucocorticoids, they still find widespread use in diseases… Continue Reading

Cushing’s Quality of Life Survey Results Presented at National Medical Meeting, 2014

Doctor's Articles | Published on: Jan 21, 2015 | Doctor's Articles, Recovery

Between January and March of 2014, the CSRF sent emails to members requesting participation in a survey on the impact of Cushing’s on quality of life. The study was also posted to the CSRF website and Facebook page. In total, 274 members completed the survey, making this one of largest studies conducted on the quality… Continue Reading

Genetic Changes Found in Cushing’s Disease, Adrenal Tumors and Adrenal Hyperplasia

Doctor's Articles | Published on: Sep 23, 2014 | Molecular Mechanism of Cushing's

Cushing’s patients often ask their physicians what caused their rare disease; they want to know if it has anything to do with their DNA and whether it can be inherited. Changes in the building blocks of genes (i.e., mutations) do indeed play a role in the development of tumors that increase adrenocorticotropic hormone (ACTH) or… Continue Reading