Question: I have a 4mm tumor on my pituitary gland and have had numerous tests showing high cortisol. An IPSS test confirmed that the pituitary gland is the problem. Unfortunately, my last several 24hr urine tests have been in the normal range. I am very symptomatic and am being told that the tumor cannot be… Continue Reading
Author Archives: kkc
Joint Replacements and Cushing’s
Question: I understand that many older patients have joint replacements due to arthritis. It seems many young Cushing’s patients also have joint replacements. Is this due to arthritis or something else? Answer: This is a great question. I have also noticed, anecdotally, that my Cushing’s patients seem to undergo more joint replacements than expected. Unfortunately… Continue Reading
Predicting Recurrence Based on Post Operative Cortisol and ACTH
Question: Is it possible to predict if a pituitary tumor will recur based on levels of cortisol and ACTH following surgery? Answer: The general answer is “no,” but studies have looked at this question in a number of ways. If a patient is in remission after transsphenoidal surgery for Cushing’s disease, the postoperative cortisol levels,… Continue Reading
Summary of The Endocrine Society Guideline on the Treatment of Cushing’s Syndrome: Part 1
Editor’s Note: Dr. Lynnette Nieman, NIH, NICHD, Bethesda, MD chaired the task force that developed the guideline. The task force also included Beverly M.K. Biller of Massachusetts General Hospital in Boston, MA; James W. Findling of the Medical College of Wisconsin in Milwaukee, WI; M. Hassan Murad of the Mayo Clinic in Rochester, MN; John… Continue Reading
Long-term Effects of Cushing’s Syndrome on Adipose Tissue Distribution
“Doctor, since I was successfully treated for Cushing’s syndrome, I have lost a lot of weight but my abdominal fat will just not go away.” This is a sentence that many endocrinologists frequently hear, and something you, as patients, may also recognize. This article will focus on the long-term effects of pituitary or adrenal Cushing’s… Continue Reading
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