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Author Archives: kkc

Exercise and Replacement Dose

Question: I am on permanent replacement steroids. Do I need to increase my dose with exercise?  Answer: Some patients remain on permanent replacement with glucocorticoid steroids because the pituitary gland is not able to produce enough ACTH (following extensive pituitary surgery for Cushing’s disease or other pituitary tumor or disease); others are on permanent replacementContinue Reading

Is One Adrenal Gland Really Enough?

Question: How has it been shown that one adrenal gland REALLY makes enough cortisol? My adrenal works, but not enough for periods of stress. What do I do?   Answer: One normal adrenal gland is able to produce sufficient amounts of cortisol, aldosterone and adrenal androgens to fulfill the body’s needs. If one adrenal glandContinue Reading

Diabetes and cholesterol after long term remission

Question: I didn’t have diabetes, high cholesterol or tri-glycerides during my Cushing’s, but have developed them after my curative surgery, which I think increases my risk for cardiovascular disease. Are those that had Cushing’s predisposed to developing these conditions later in life?   Answer: It is well known that active Cushing’s increases the risk forContinue Reading

Preventing and Treating an Adrenal crisis

Have you ever had an adrenal crisis? If you have experienced the pain, confusion, nausea, vomiting, rapid heartbeat, low blood pressure, weakness and other disturbing symptoms, you know you need help right away. Without immediate correct treatment, an adrenal crisis can be life-threatening. A recent review (1) reports “Studies in patients on chronic replacement therapyContinue Reading

Androgen Replacement Therapy in Women with Adrenal Insufficiency

INTRODUCTION Androgen levels are lower in women with adrenal insufficiency than in healthy women of comparable age. This raises the question of whether testosterone or DHEA replacement therapy should be part of the standard hormone replacement therapy regimens prescribed to women with adrenal insufficiency, including in patients with a history of Cushing’s syndrome. WHAT AREContinue Reading

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