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ACTH Stimulation Test to Determine Discontinuation of Steroid Replacement

Question: What is an ACTH Stimulation Test and what is it used for? Answer: An ACTH stimulation test is most commonly used in patients with Cushing’s Syndrome many months after surgery to determine whether their hypothalamic-pituitary-adrenal axis is recovering and whether it is therefore safe to discontinue their steroid medications. It is a 1 hourContinue Reading

Pregnancy After Cushing’s

Question: Is it possible to become pregnant and have a normal pregnancy after having had Cushing’s syndrome? Answer: Assuming that the treatment of the Cushing’s syndrome has not interfered with reproductive function (e.g., that the neurosurgeon has not removed so much of the pituitary gland that it cannot secrete normal amounts of follicle-stimulating hormone (FSH)Continue Reading

Pituitary Radiation and Pregnancy

Question: Will radiation of the pituitary gland cause problems for females wanting to have children? If so, how long will it take for the problem to become apparent? Answer: Radiation treatment to the pituitary gland may result in pituitary gland hypofunction over a several year period of time. In the first 10 years after pituitaryContinue Reading

Menopause Symptoms and Cushing’s

Question: Are menopause symptoms more pronounced in someone who has had Cushing’s? Answer: Menopausal symptoms vary enormously from one woman to another and symptoms are often genetically determined. Some woman have almost no symptoms and other woman have significant symptoms that go on for years. Woman who have had Cushing’s do not in general experienceContinue Reading

Menopause Hormone Replacement Therapy

Question: I had Cushing’s a number of years ago and completely recovered. Due to menopause, I started hormone replacement therapy (HRT) and I feel like some of my Cushing’s symptoms have returned. Can side effects from HRT mimic Cushing’s symptoms? Answer: In menopausal patients, HRT, when given for a short-time typically leads to significant improvementContinue Reading

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