Question: How many Cushing’s patients continue to complain of fatigue, depression, aches and pains many years after their Cushing’s has been cured? Answer: Cushing’s syndrome is a difficult disease to manage. In the best of circumstances, patients feel back to baseline after curative surgery and subsequent steroid taper. In patients who continue to feel fatigue,… Continue Reading
Author Archives: kkc
Aches and Pains During Illness
Question: I had a pituitary tumor removed and am no longer on replacement medication. It seems that even something minor, like a cold, causes havoc with my system, including aches and pains. Is this normal after having had Cushing’s? Answer: Following the removal of an ACTH secreting pituitary tumor (or an adrenal cortisol secreting tumor),… Continue Reading
Importance of an Expert Pituitary Surgeon
Question: I have Cushing’s Disease and my doctor insists that I travel to a major medical center to have surgery. Why is it so important to have an expert pituitary neurosurgeon? Answer: The success in curing a patient of Cushing’s Disease is directly related to the experience of the neurosurgeon. In other words, it is… Continue Reading
Recurrence Rates for Cushing’s Disease
Question: What is the recurrence rate for Cushing’s Disease? Answer: Transsphenoidal surgery is the initial treatment of choice for most patients with proved or highly suspected Cushing’s disease. Published reports demonstrate that, in experienced centers, remission following surgery can be expected in 80-90% of patients with microadenomas and 50-65% of patients with macroadenomas. Recurrent hypercortisolism… Continue Reading
What is Nelson’s Syndrome?
Question: What is Nelson’s syndrome? Answer: Up to 10% of patients who have had a bilateral adrenalectomy for the cure of pituitary Cushing’s can develop Nelson’s syndrome. This syndrome refers to the enlargement of the pituitary tumor after removal of both adrenal glands. Bilateral adrenalectomy was the primary treatment for pituitary Cushing’s prior to the… Continue Reading
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