Question: What is a petrosal sinus sampling test, how is it done, and when is it used? Answer: The majority of patients with Cushing’s syndrome have an ACTH-secreting tumor (pituitary or nonpituitary) causing both adrenal glands to produce excessive amounts of cortisol. Although the majority of patients have pituitary tumors, approximately 10-15% of patients have… Continue Reading

Question: Is testing for Cushing’s more difficult and can some tests come back normal when you haven’t had Cushing’s very long? Answer: As with most conditions, if the diagnosis is obvious clinically, then biochemical confirmation is usually simple; if the diagnosis is not clear, then biochemical confirmation or exclusion of the diagnosis is often much… Continue Reading