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A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ATR-101 for the Treatment of Cushing’s Syndrome

“A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ATR-101 for the Treatment of Cushing’s Syndrome” is a study for adults with Cushing’s Syndrome and is sponsored by Millendo Therapeutics, Inc. This study will evaluate the efficacy and safety of ATR-101 which is an oral study medication for the treatment of endogenous Cushing’s syndrome. The study will follow patients for up to 20 weeks including a screening period of up to 8 weeks, 6-week open-label treatment with increasing doses of study medication, 4-week double-blinded withdrawal period with study medication or placebo, and a 2 week follow-up period.

Patients should meet the following requirements to participate:

  • Confirmed diagnosis of endogenous Cushing’s syndrome with elevated urinary free cortisol
  • BMI 18-45 kg/m2
  • If previous pituitary surgery, patients must be at least 6 months since surgery at the time of screening
  • Radiotherapy within 1 year prior to or during the screening period is excluded
  • Patients who are eligible for surgical treatment of Cushing’s syndrome are excluded, unless surgery is not anticipated to occur during the study

Further information is available at clinicaltrials.gov: NCT03053271

 

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A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ATR-101 for the Treatment of Cushing’s Syndrome

“A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ATR-101 for the Treatment of Cushing’s Syndrome” is a study for adults with Cushing’s Syndrome and is sponsored by Millendo Therapeutics, Inc. This study will evaluate the efficacy and safety of ATR-101 which is an oral study medication for the treatment of endogenous Cushing’s syndrome. The studyContinue Reading

Sorry, comments are closed for this post.