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Clinical Trials

This page includes a review of current studies and resources for patients looking for more information on clinical trials for Cushing’s Disease and Cushing’s Syndrome. It will be updated as new studies come to our attention.

National Institute of Health Clinical Studies

The National Institute of Health has ongoing research studies involving Cushing’s. If patients fit into an existing research protocol, evaluation and treatment is free of charge.Continue Reading

Research Study: An Open Label Study to Evaluate CORT125134 in Patients with Cushing Syndrome

Objectives:The purpose of this study is to evaluate a new investigational medication for patients who have Cushing syndrome due to the body’s production of too much cortisol.This study is an open label study. That means both the health providers and the participants in the study are aware of the drug or treatment being given.This isContinue Reading

Are You Living with Endogenous Cushing’s Syndrome?

Now looking for volunteers to participate in SONICS, a clinical study for an investigational drug (COR-003). The purpose of the study is to test the safety and efficacy of COR-003 in the treatment of endogenous Cushing’s syndrome. This study is open-label, which means both the health providers and the participants in the study are aware of the drug or treatment being given. Information from this study will also help doctors learn more about COR-003 in treating endogenous Cushing’s syndrome.Continue Reading

A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ATR-101 for the Treatment of Cushing’s Syndrome

“A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of ATR-101 for the Treatment of Cushing’s Syndrome” is a study for adults with Cushing’s Syndrome and is sponsored by Millendo Therapeutics, Inc. This study will evaluate the efficacy and safety of ATR-101 which is an oral study medication for the treatment of endogenous Cushing’s syndrome. The studyContinue Reading

Treatment of Cushing’s Disease With R-roscovitine – A Phase 2 Study

The investigators hypothesize that R-roscovitine will suppress pituitary corticotroph tumor ACTH production and normalize urinary free cortisol levels in patients with Cushing disease. To date, R-roscovitine has been evaluated in several Phase I and II studies and has shown early signs of anti-cancer activity in approximately 240 patients.Location: Pituitary Center, Cedars-Sinai Medical Center, Los Angeles, CAPrincipalContinue Reading